Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 20/20 | 0.77 |
| ▸ | FYN | P06241 | 1/20 | 0.66 |
| ▸ | SRC | P12931 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6058023 | 0.91 | LCK (0.83) | LCKFYNSRC | |
| SCHEMBL6057876 | 0.91 | LCK (0.85) | LCKFYNSRC | |
| SCHEMBL6057763 | 0.89 | LCK (0.80) | LCKFYNSRC | |
| SCHEMBL6058189 | 0.89 | LCK (0.80) | LCKFYNSRC | |
| SCHEMBL6058056 | 0.88 | LCK (0.81) | LCKFYNSRC | |
| SCHEMBL6058193 | 0.88 | LCK (0.87) | LCKFYNSRC | |
| SCHEMBL6057971 | 0.88 | LCK (0.87) | LCKFYNSRC | |
| SCHEMBL6058025 | 0.88 | LCK (0.78) | LCKFYNSRC | |
| SCHEMBL6058108 | 0.88 | LCK (0.86) | LCKFYNSRC | |
| SCHEMBL6057657 | 0.87 | LCK (0.83) | LCKFYNSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825355-B2 | FOR THERAPY OF IMMUNOLOGIC DISORDERS SUCH AS TRANSPLANT REJECTION, RHEUMATOID ARTHRITIS. MULTIPLE SCLEROSIS, INFLAMMATORY BOWEL DISEASE, LUPUS, GRAFT VS. HOST DISEASE | BRISTOL-MYERS SQUIBB CO. | 2004-11-30 | — | — | US | disclosed |