Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 11/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515961 | 1.00 | GRM2 (0.63) | GRM2SMN1; SMN2NPSR1KMT2APOLB | |
| SCHEMBL6903048 | 0.85 | GRM2 (0.62) | GRM2SMN1; SMN2NPSR1KMT2APOLB | |
| SCHEMBL6903794 | 0.84 | GRM2 (0.62) | GRM2SMN1; SMN2NPSR1KMT2APOLB | |
| SCHEMBL1516082 | 0.84 | GRM2 (0.62) | GRM2SMN1; SMN2NPSR1KMT2APOLB | |
| SCHEMBL1513447 | 0.83 | GRM2 (0.62) | GRM2SMN1; SMN2NPSR1KMT2APOLB | |
| SCHEMBL1513224 | 0.83 | GRM2 (0.72) | GRM2SMN1; SMN2NPSR1KMT2APOLB | |
| SCHEMBL1513227 | 0.83 | GRM2 (0.72) | GRM2SMN1; SMN2NPSR1KMT2APOLB | |
| SCHEMBL1495903 | 0.82 | GRM2 (0.72) | GRM2SMN1; SMN2NPSR1KDM4EMAPT | |
| SCHEMBL3143447 | 0.82 | GRM2 (0.72) | GRM2SMN1; SMN2NPSR1KDM4EMAPT | |
| SCHEMBL3144375 | 0.82 | GRM2 (0.72) | GRM2SMN1; SMN2NPSR1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034832-A1 | SUBSTITUTED PHENOXYMETHYL DIHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-03-24 | — | — | WO | disclosed |