SCHEMBL6905102

SCHEMBL6905102

Cc1ccc(C2=Cc3c(-c4ccc(C(C)(C)C)cc4)cccc3C2[Hf]C2C(c3ccc(C)o3)=Cc3c(-c4ccc(C(C)(C)C)cc4)cccc32)o1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.31
CREBBP Q92793 1/20 0.31
S1PR1 P21453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6901745 0.88 NQO2 (0.36) S1PR1
SCHEMBL6897870 0.86 CHRM2 (0.32)
SCHEMBL28574931 0.85 BRD4 (0.32) BRD4CREBBPS1PR1
SCHEMBL28572062 0.85 BRD4 (0.32) BRD4CREBBPS1PR1
SCHEMBL3081243 0.84 S1PR1 (0.33) BRD4CREBBPS1PR1
SCHEMBL6901142 0.84 S1PR1 (0.33) BRD4CREBBPS1PR1
SCHEMBL6904755 0.84
Hydrochloric Acid SCHEMBL6902390 0.83 BRD4 (0.31) BRD4CREBBPS1PR1
Hydrochloric Acid SCHEMBL6897986 0.83 BRD4 (0.31) BRD4CREBBPS1PR1
Hydrochloric Acid SCHEMBL6901335 0.83 BRD4 (0.31) BRD4CREBBPS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1033371-B1 Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins BASELL POLYOLEFINE GMBH (DE) 2004-01-28 EP claimed