Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625607 | 1.00 | MAPK1 (0.42) | MAPK1KDM4ENPSR1RXFP1TSHR | |
| SCHEMBL4626509 | 0.91 | TSHR (0.46) | MAPK1KDM4ENPSR1RXFP1TSHR | |
| SCHEMBL4625817 | 0.89 | TSHR (0.47) | MAPK1KDM4ETSHRCRHBPCRHR2 | |
| SCHEMBL4626925 | 0.89 | TSHR (0.50) | MAPK1KDM4ENPSR1RXFP1TSHR | |
| SCHEMBL6910969 | 0.87 | MAPK1 (0.43) | MAPK1KDM4ENPSR1RXFP1TSHR | |
| SCHEMBL4628623 | 0.87 | MAPK1 (0.43) | MAPK1KDM4ENPSR1RXFP1TSHR | |
| Ethane SCHEMBL4639959 | 0.85 | HSD17B10 (0.39) | TSHRCA12CA1CA2CA9 | |
| Ethane SCHEMBL4639984 | 0.85 | HSD17B10 (0.39) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL4628625 | 0.85 | KDM4E (0.41) | MAPK1KDM4ENPSR1RXFP1TSHR | |
| SCHEMBL4626483 | 0.85 | KDM4E (0.41) | MAPK1KDM4ENPSR1RXFP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770586-B2 | Solid catalyst component and catalyst for olefins polymerization | TOHO TITANIUM CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |