Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908948 | 1.00 | ESR1 (0.48) | ESR1TSHRTDP1L3MBTL1ATM | |
| SCHEMBL4626902 | 0.95 | ESR1 (0.39) | ESR1TSHRTDP1L3MBTL1ATM | |
| SCHEMBL4628147 | 0.93 | ESR1 (0.40) | ESR1TSHRTDP1L3MBTL1ATM | |
| SCHEMBL4626641 | 0.92 | ESR1 (0.52) | ESR1TSHRTDP1L3MBTL1ATM | |
| SCHEMBL4627559 | 0.90 | TSHR (0.53) | ESR1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4626618 | 0.90 | ESR1 (0.56) | ESR1TSHRTDP1L3MBTL1ATM | |
| SCHEMBL4627576 | 0.90 | ESR1 (0.48) | ESR1TSHRTDP1L3MBTL1ATM | |
| SCHEMBL4627115 | 0.89 | TSHR (0.40) | ESR1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4628596 | 0.87 | ESR1 (0.48) | ESR1TSHRTDP1L3MBTL1ATM | |
| SCHEMBL4625668 | 0.87 | ESR1 (0.48) | ESR1TSHRTDP1L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770586-B2 | Solid catalyst component and catalyst for olefins polymerization | TOHO TITANIUM CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |