Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 20/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466495 | 0.88 | GRIN1 (0.77) | GRIN1 | |
| SCHEMBL7471518 | 0.88 | GRIN1 (0.77) | GRIN1 | |
| SCHEMBL7469516 | 0.88 | GRIN1 (0.74) | GRIN1 | |
| SCHEMBL7586603 | 0.87 | GRIN1 (0.79) | GRIN1 | |
| SCHEMBL7461136 | 0.85 | GRIN1 (0.72) | GRIN1 | |
| SCHEMBL7465495 | 0.84 | GRIN1 (1.00) | GRIN1 | |
| SCHEMBL7467247 | 0.83 | GRIN1 (1.00) | GRIN1 | |
| SCHEMBL7474408 | 0.83 | GRIN1 (0.69) | GRIN1 | |
| SCHEMBL7466031 | 0.82 | GRIN1 (0.67) | GRIN1 | |
| SCHEMBL7461236 | 0.81 | GRIN1 (0.77) | GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783495-B1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER LTD (GB) | 2002-02-27 | — | — | EP | claimed |
| EP-0784973-B1 | Quinoxaline derivatives for treating tinnitus | PFIZER (US) | 2002-02-06 | — | — | EP | claimed |
| JP-2986920-B2 | — | — | 1999-12-06 | — | — | JP | claimed |
| US-5852016-A | Quinoxaline derivatives useful in therapy | PFIZER INC. (US) | 1998-12-22 | — | — | US | claimed |
| US-5840723-A | Quinoxaline derivatives for treating tinnitus | PFIZER INC. (US) | 1998-11-24 | — | — | US | claimed |
| EP-0784973-A2 | Quinoxaline derivatives for treating tinnitus | PFIZER INC. (US) | 1997-07-23 | — | — | EP | claimed |
| EP-0783495-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | Pfizer Limited (GB) | 1997-07-16 | — | — | EP | claimed |
| WO-1996009295-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER LIMITED (GB) | 1996-03-28 | — | — | WO | claimed |
| JP-9132530-A | — | — | None | — | — | JP | disclosed |
| US-20250302825-A1 | COMBINATION TREATMENTS FOR DEPRESSION UTILIZING AN NMDAR ANTAGONIST | GLYTECH LLC (US) | 2025-10-02 | — | — | US | disclosed |
| US-20250144090-A1 | COMPOSITION AND METHOD FOR TREATMENT OF DEPRESSION AND PSYCHOSIS IN HUMANS | GLYTECH LLC (US) | 2025-05-08 | — | — | US | disclosed |
| EP-3630103-B1 | COMBINED THERAPY FOR NMDAR ANTAGONIST-RESPONSIVE NEUROPSYCHIATRIC DISORDERS | GLYTECH LLC (US) | 2024-10-30 | — | — | EP | disclosed |
| US-20240277728-A1 | FORMULATIONS FOR TREATMENT OF POST-TRAUMATIC STRESS DISORDER | GLYTECH LLC (US) | 2024-08-22 | — | — | US | disclosed |
| US-11969431-B2 | Formulations for treatment of post-traumatic stress disorder | GLYTECH LLC (US) | 2024-04-30 | — | — | US | disclosed |
| EP-0784973-B1 | Quinoxaline derivatives for treating tinnitus | PFIZER (US) | 2002-02-06 | — | — | EP | disclosed |
| US-5852016-A | Quinoxaline derivatives useful in therapy | PFIZER INC. (US) | 1998-12-22 | — | — | US | disclosed |
| US-5840723-A | Quinoxaline derivatives for treating tinnitus | PFIZER INC. (US) | 1998-11-24 | — | — | US | disclosed |
| EP-0784973-A2 | Quinoxaline derivatives for treating tinnitus | PFIZER INC. (US) | 1997-07-23 | — | — | EP | disclosed |
| JP-H09132530-A | QUINOXALINE DERIVATIVE FOR TREATING TINNITUS | PFIZER INC | 1997-05-20 | — | — | JP | disclosed |
| WO-1996009295-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER LIMITED (GB) | 1996-03-28 | — | — | WO | disclosed |