Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094543 | 0.87 | MAPT (0.49) | MAPTALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL1648606 | 0.83 | MAPT (0.49) | MAPTALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL7798997 | 0.78 | MAPT (0.44) | MAPTALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL2919381 | 0.77 | TP53 (0.51) | MAPTALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL1648605 | 0.75 | TSHR (0.43) | MAPTALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL4938672 | 0.74 | TP53 (0.51) | MAPTALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL17982633 | 0.74 | TP53 (0.51) | MAPTALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL3085264 | 0.74 | MAPT (0.43) | MAPTALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL18817713 | 0.73 | TP53 (0.54) | MAPTALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL3093196 | 0.73 | MAPT (0.49) | MAPTALDH1A1TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174467-B1 | Heat stable, corrosion inhibiting polyorganosiloxane resins | GOLDSCHMIDT AG TH (DE) | 2004-09-15 | — | — | EP | claimed |
| US-6528607-B2 | Process control; controlling temperature | GOLDSCHMIDT AG (DE) | 2003-03-04 | — | — | US | disclosed |
| US-20020028296-A1 | Heat-stable, corrosion-inhibiting polyorganosiloxane resins | EVONIK DEGUSSA GMBH (DE) | 2002-03-07 | — | — | US | disclosed |
| US-4452961-A | Process for the synthesis of heat-curable silicone resins | TH. GOLDSCHMIDT AG (DE) | 1984-06-05 | — | — | US | disclosed |