Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5931958 | 0.99 | SLC6A4 (0.34) | SLC6A4SLC6A2MAPK1HSD17B10POLQ | |
| SCHEMBL6414489 | 0.80 | BCL2 (0.45) | SLC6A4SLC6A2MAPK1HSD17B10FLT3 | |
| SCHEMBL2074588 | 0.80 | BCL2 (0.45) | SLC6A4SLC6A2MAPK1HSD17B10FLT3 | |
| Hydrochloric Acid SCHEMBL6404976 | 0.79 | BCL2 (0.44) | SLC6A4SLC6A2MAPK1HSD17B10FLT3 | |
| SCHEMBL6570235 | 0.74 | MAPK1 (0.34) | SLC6A4SLC6A2MAPK1HSD17B10POLQ | |
| SCHEMBL8297599 | 0.71 | SLC6A4 (0.37) | SLC6A4POLQFLT3TAAR1KCNH2 | |
| SCHEMBL7380040 | 0.68 | BCL2 (0.61) | SLC6A4SLC6A2MEN1KMT2AKCNH2 | |
| SCHEMBL27778749 | 0.68 | MAPK1 (0.34) | SLC6A4SLC6A2MAPK1HSD17B10 | |
| SCHEMBL23333193 | 0.67 | BCL2 (0.46) | POLQMEN1KMT2AKCNH2 | |
| SCHEMBL28444599 | 0.66 | BCL2 (0.58) | SLC6A4KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812355-B2 | INVOLVING TWO SUCCESSIVE GRIGNARD REACTIONS; EMPLOYING LEWIS ACID TO REDUCING BY-PRODUCT FORMATION | SEKHSARIA CHEMICALS LIMITED (IN) | 2004-11-02 | — | — | US | disclosed |
| EP-1288211-A1 | Improved process for the manufacture of citalopram hydrobromide from 5-bromophthalide | Sekhsaria Chemicals Ltd. (IN) | 2003-03-05 | — | — | EP | disclosed |