Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL27460518 | 1.00 | TSHR (0.55) | TSHRFFAR3CES2CES1L3MBTL1 | |
| Chlorobenzene SCHEMBL28177257 | 0.98 | TSHR (0.52) | TSHRFFAR3CES2CES1L3MBTL1 | |
| Chlorobenzene SCHEMBL27685704 | 0.98 | TSHR (0.52) | TSHRFFAR3CES2CES1L3MBTL1 | |
| 1,4-Dichlorobenzene SCHEMBL27561831 | 0.90 | FFAR3 (0.56) | TSHRFFAR3CES2CES1L3MBTL1 | |
| Chlorobenzene SCHEMBL27681928 | 0.89 | TSHR (0.44) | TSHRFFAR3CES2CES1L3MBTL1 | |
| Chlorobenzene SCHEMBL11754331 | 0.88 | TSHR (0.52) | TSHRCES2CES1L3MBTL1MAPT | |
| Chlorobenzene SCHEMBL27545797 | 0.88 | TSHR (0.52) | TSHRCES2CES1L3MBTL1MAPT | |
| Chlorobenzene SCHEMBL27453116 | 0.88 | TSHR (0.52) | TSHRCES2CES1L3MBTL1MAPT | |
| Chlorobenzene SCHEMBL27484105 | 0.88 | TSHR (0.42) | TSHRFFAR3CES2CES1L3MBTL1 | |
| Chlorobenzene SCHEMBL27801045 | 0.86 | TSHR (0.50) | TSHRCES2CES1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910001-A | Synthetic method of 5-chloro-1-indanone | XU WEI | 2015-09-16 | — | — | CN | claimed |
| CN-110294659-A | A kind of preparation method of organic carboxyl acid | 中国科学院兰州化学物理研究所苏州研究院 | 2019-10-01 | — | — | CN | disclosed |
| CN-109678718-A | The method of ionic liquid-catalyzed synthetic styrene-acrylic acid esters analog derivative | 江西师范大学 | 2019-04-26 | — | — | CN | disclosed |
| CN-104910001-B | A kind of synthetic method of the chloro- 1- indones of new 5- | 上海博栋化学科技有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-104910001-B | A kind of synthetic method of the chloro- 1- indones of new 5- | 上海博栋化学科技有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-108424367-A | A kind of method that propiolic acid and its derivative are prepared under temperate condition | 中国科学院化学研究所 | 2018-08-21 | — | — | CN | disclosed |
| CN-105854938-B | Polystyrene supported catalyst and application method thereof in synthesis of dihydrocoumarin | 江苏新淮河医药科技有限公司 | 2018-03-09 | — | — | CN | disclosed |
| CN-107759460-A | A kind of method for preparing the more acid monomers of polyphenyls | 朱翠英 | 2018-03-06 | — | — | CN | disclosed |
| CN-107353194-A | A kind of preparation method of propine acid compounds | 大连理工大学 | 2017-11-17 | — | — | CN | disclosed |
| CN-107207483-A | Alpha-amino-beta-carboxymuconate semialdehyde decarboxylase inhibitors | TES制药有限责任公司 | 2017-09-26 | — | — | CN | disclosed |
| US-5849769-A | N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection | MEDIVIR AB (SE) | 1998-12-15 | — | — | US | disclosed |
| EP-0706514-B1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1998-11-18 | — | — | EP | disclosed |
| EP-0706514-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1996-04-17 | — | — | EP | disclosed |
| EP-0419049-B1 | (Quinolin-2-ylmethoxy) indoles as inhibitors of the biosynthesis of leukotrienes | MERCK FROSST CANADA INC (CA) | 1995-04-12 | — | — | EP | disclosed |
| WO-1995006034-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1995-03-02 | — | — | WO | disclosed |
| US-5380850-A | Quinoline hydrazine intermediates | MERCK FROSST CANADA, INC. (CA) | 1995-01-10 | — | — | US | disclosed |
| WO-1994013293-A2 | (QUINOLIN-2-YLMETHOXY)INDOLES AS INHIBITORS OF THE BIOSYNTHESIS OF LEUKOTRIENES | MERCK FROSST CANADA INC. (CA) | 1994-06-23 | — | — | WO | disclosed |
| US-5272145-A | (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes | MERCK FROSST CANADA, INC. (CA) | 1993-12-21 | — | — | US | disclosed |
| US-5204344-A | (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes | MERCK FROSST CANADA, INC. (CA) | 1993-04-20 | — | — | US | disclosed |
| EP-0419049-A1 | (Quinolin-2-ylmethoxy) indoles as inhibitors of the biosynthesis of leukotrienes | MERCK FROSST CANADA INC. (CA) | 1991-03-27 | — | — | EP | disclosed |