Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.42 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.42 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889755 | 0.78 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL7765863 | 0.77 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL29405044 | 0.77 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| SCHEMBL10414766 | 0.77 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| SCHEMBL50148 | 0.77 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3410866 | 0.75 | CA1 (0.57) | CA1CA2CA7CA9CA12 | |
| Hydrochloric Acid SCHEMBL7972166 | 0.75 | CA1 (0.57) | CA1CA2CA7CA9CA12 | |
| SCHEMBL15658840 | 0.75 | CA1 (0.57) | CA1CA2CA7CA9CA12 | |
| SCHEMBL8419557 | 0.75 | CA1 (0.57) | CA1CA2CA7CA9CA12 | |
| SCHEMBL5713309 | 0.75 | CA1 (0.57) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6717011-B1 | ASYMMETRIC SYNTHESIS CATALYSTS | STYLACATS LIMITED (GB) | 2004-04-06 | — | — | US | disclosed |
| EP-1155024-A1 | CHIRAL DIAZAPHOSPHOLIDINE LIGANDS | The University of Warwick (GB) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050430-A1 | CHIRAL DIAZAPHOSPHOLIDINE LIGANDS | THE UNIVERSITY OF WARWICK (GB) | 2000-08-31 | — | — | WO | disclosed |