Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10765977 | 1.00 | MEN1 (0.38) | MEN1KMT2ATSHR | |
| SCHEMBL28323877 | 1.00 | MEN1 (0.38) | MEN1KMT2ATSHR | |
| SCHEMBL459271 | 0.93 | TSHR (0.39) | MEN1KMT2ATSHR | |
| 2-Bromoethanol SCHEMBL3055303 | 0.88 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL8645521 | 0.87 | KMT2A (0.51) | MEN1KMT2ATSHR | |
| SCHEMBL9879608 | 0.87 | KMT2A (0.51) | MEN1KMT2ATSHR | |
| SCHEMBL11818110 | 0.81 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL9661524 | 0.81 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL10344326 | 0.80 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL14151007 | 0.80 | KMT2A (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943328-B1 | Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia | ENDORECH INC (CA) | 2004-06-16 | — | — | EP | disclosed |
| EP-0595796-B1 | METHOD OF TREATMENT OF ANDROGEN-RELATED DISEASES | ENDORECH INC (CA) | 2003-01-15 | — | — | EP | disclosed |
| US-6423698-B1 | ADMINISTERING INHIBITOR OF 17-BETA-HYDROXYSTEROID DEHYDROGENASE AND AT LEAST ONE OF AN INHIBITOR OF AROMATASE AND INHIBITOR OF 5-ALPHA-REDUCTASE | ENDORECHERCHE, INC. (CA) | 2002-07-23 | — | — | US | disclosed |
| US-6110906-A | ANDROGEN RECEPTOR ANTAGONISTS, ANTICARCINOGENIC AGENTS; PROSTATE CANCER | ENDORECHERCHE, INC. (CA) | 2000-08-29 | — | — | US | disclosed |
| EP-0943328-A2 | Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia | ENDORECHERCHE INC. (CA) | 1999-09-22 | — | — | EP | disclosed |
| EP-0480950-B1 | COMBINATION THERAPY FOR PROPHYLAXIS AND/OR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | ENDORECHERCHE INC (CA) | 1999-03-24 | — | — | EP | disclosed |
| US-5817649-A | Combination therapy for the prophylaxis and/or treatment of benign prostatic hyperplasia | ENDORECHERCHE, INC. (CA) | 1998-10-06 | — | — | US | disclosed |
| EP-0485392-B1 | ANDROGEN DERIVATIVES FOR USE IN THE INHIBITION OF SEX STEROID ACTIVITY | ENDORECHERCHE INC (CA) | 1998-09-09 | — | — | EP | disclosed |
| EP-0857487-A2 | Combinations for prophylaxsis and/or treatment of benign prostatic hyperplasia containing a 17 beta-hydroxy steroid dehydrogenase (17bHSD) inhibitor and at least one further active ingredient | ENDORECHERCHE INC. (CA) | 1998-08-12 | — | — | EP | disclosed |
| US-5610150-A | Method of treatment of androgen-related diseases | ENDORECHERCHE INC. (CA) | 1997-03-11 | — | — | US | disclosed |
| US-5372996-A | Method of treatment of androgen-related diseases | ENDORECHERCHE, INC. (CA) | 1994-12-13 | — | — | US | disclosed |
| EP-0615448-A1 | SEX STEROID ACTIVITY INHIBITORS | ENDORECHERCHE INC. (CA) | 1994-09-21 | — | — | EP | disclosed |
| EP-0595796-A1 | METHOD OF TREATMENT OF ANDROGEN-RELATED DISEASES | ENDORECHERCHE INC. (CA) | 1994-05-11 | — | — | EP | disclosed |
| WO-1993010741-A2 | SEX STEROID ACTIVITY INHIBITORS | ENDORECHERCHE INC. (CA) | 1993-06-10 | — | — | WO | disclosed |
| EP-0485392-A1 | ANDROGEN DERIVATIVES FOR USE IN THE INHIBITION OF SEX STEROID ACTIVITY | ENDORECHERCHE INC. (CA) | 1992-05-20 | — | — | EP | disclosed |
| EP-0480950-A1 | COMBINATION THERAPY FOR PROPHYLAXIS AND/OR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | ENDORECHERCHE INC. (CA) | 1992-04-22 | — | — | EP | disclosed |
| WO-1991000731-A1 | COMBINATION THERAPY FOR PROPHYLAXIS AND/OR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | ENDORECHERCHE INC. (CA) | 1991-01-24 | — | — | WO | disclosed |
| WO-1991000733-A1 | METHOD OF TREATMENT OF ANDROGEN-RELATED DISEASES | ENDORECHERCHE INC. (CA) | 1991-01-24 | — | — | WO | disclosed |
| WO-1991000732-A1 | ANDROGEN DERIVATIVES FOR USE IN THE INHIBITION OF SEX STEROID ACTIVITY | ENDORECHERCHE INC. (CA) | 1991-01-24 | — | — | WO | disclosed |
| US-4243660-A | 11-HEXADECENYL AND 11-HEPTADECENYL ACETATE; SYNERGISTIC | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1981-01-06 | — | — | US | disclosed |