Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.55 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.55 |
| ▸ | ATG7 | O95352 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.46 |
| ▸ | TYMP | P19971 | 1/20 | 0.46 |
| ▸ | DTYMK | P23919 | 2/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13268677 | 0.90 | POLB (0.58) | POLBENPP1P2RY1ATG7HIF1A | |
| SCHEMBL1140597 | 0.88 | POLB (0.58) | POLBENPP1P2RY1ATG7HIF1A | |
| SCHEMBL1140505 | 0.88 | POLB (0.60) | POLBENPP1P2RY1ATG7HIF1A | |
| SCHEMBL13269208 | 0.83 | POLB (0.53) | POLBENPP1P2RY1ATG7HIF1A | |
| SCHEMBL13268821 | 0.83 | POLB (0.54) | POLBENPP1P2RY1ATG7HIF1A | |
| SCHEMBL16359945 | 0.81 | POLB (0.67) | POLBENPP1P2RY1HIF1AADORA1 | |
| SCHEMBL439242 | 0.81 | POLB (0.67) | POLBENPP1P2RY1HIF1AADORA1 | |
| SCHEMBL10021398 | 0.81 | POLB (0.67) | POLBENPP1P2RY1HIF1AADORA1 | |
| SCHEMBL24370817 | 0.81 | POLB (0.61) | POLBENPP1P2RY1HIF1AADORA1 | |
| SCHEMBL31098256 | 0.81 | POLB (0.61) | POLBENPP1P2RY1HIF1AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866071-B1 | Modified primers | HOFFMANN LA ROCHE (CH) | 2004-10-20 | — | — | EP | disclosed |
| EP-0866071-A2 | Modified primers | F. HOFFMANN-LA ROCHE AG (CH) | 1998-09-23 | — | — | EP | disclosed |