Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93558 | 0.92 | TDP1 (0.48) | TDP1USP2CYP3A4MAPTLMNA | |
| SCHEMBL93559 | 0.92 | TDP1 (0.48) | TDP1USP2CYP3A4MAPTLMNA | |
| SCHEMBL28104973 | 0.80 | TDP1 (0.39) | TDP1USP2CYP3A4MAPTLMNA | |
| Acetic Acid Isobutyl Ester SCHEMBL27530275 | 0.79 | TSHR (0.61) | TDP1USP2CYP3A4MAPTLMNA | |
| SCHEMBL7164222 | 0.79 | TDP1 (0.42) | TDP1USP2CYP3A4MAPTLMNA | |
| SCHEMBL13392782 | 0.78 | USP2 (0.41) | TDP1USP2CYP3A4MAPTLMNA | |
| SCHEMBL8158162 | 0.77 | USP2 (0.41) | TDP1USP2CYP3A4MAPTLMNA | |
| Glycerin SCHEMBL15282002 | 0.76 | USP2 (0.40) | TDP1USP2CYP3A4MAPTLMNA | |
| SCHEMBL17891320 | 0.76 | TSHR (0.36) | TDP1USP2CYP3A4MAPTLMNA | |
| SCHEMBL15282001 | 0.75 | CA1 (0.42) | TDP1USP2CYP3A4MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699931-B2 | DURABILITY, CHEMICAL RESISTANCE, WEATHERPROOFING | EASTMAN CHEMICAL COMPANY | 2004-03-02 | — | — | US | claimed |
| US-20030018110-A1 | Modified alkyd compositions comprising diol latex compositions and processes of making the same | EASTMAN CHEMICAL COMPANY | 2003-01-23 | — | — | US | claimed |