Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158705 | 0.74 | — | — | |
| SCHEMBL6158700 | 0.74 | — | — | |
| SCHEMBL4797286 | 0.71 | NPC1 (0.45) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL28825040 | 0.71 | — | — | |
| SCHEMBL6910666 | 0.71 | NPC1 (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL1899602 | 0.71 | NPC1 (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL13010156 | 0.70 | NPC1 (0.31) | NPC1RAB9A | |
| SCHEMBL22055452 | 0.69 | — | — | |
| SCHEMBL317174 | 0.69 | — | — | |
| SCHEMBL6158672 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079114-A1 | PTERIDINONES AS INHIBITORS OF POLO - LIKE KINASE | ELAN PHARMACEUTICALS, INC. (US) | 2011-06-30 | — | — | WO | disclosed |