⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17628450 | 1.00 | — | — | |
| SCHEMBL17628431 | 0.97 | — | — | |
| SCHEMBL30497683 | 0.89 | TSHR (0.44) | — | |
| SCHEMBL20536318 | 0.89 | — | — | |
| SCHEMBL30497682 | 0.89 | TSHR (0.44) | — | |
| SCHEMBL25241378 | 0.89 | TSHR (0.44) | — | |
| SCHEMBL30497681 | 0.89 | TSHR (0.44) | — | |
| SCHEMBL10824855 | 0.89 | TSHR (0.44) | — | |
| SCHEMBL7212251 | 0.89 | TSHR (0.44) | — | |
| SCHEMBL4521741 | 0.89 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311935-A1 | MOISTURE CURABLE MATERIALS FOR DELIVERY OF AGENTS, METHODS, AND MEDICAL DEVICES | MEDTRONIC, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| US-7776351-B2 | Moisture curable materials for delivery of agents, methods, and medical devices | MEDTRONIC, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-20040054113-A1 | Polymers with soft segments containing silane-containing groups, medical devices, and methods | MEDTRONIC, INC. | 2004-03-18 | — | — | US | disclosed |