Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909381 | 0.94 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL6908038 | 0.90 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL6908142 | 0.87 | HCRTR1 (0.44) | HCRTR1HCRTR2PTPN11 | |
| SCHEMBL6908966 | 0.81 | HCRTR1 (0.44) | HCRTR1HCRTR2PTPN11 | |
| SCHEMBL1586923 | 0.80 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL6908698 | 0.80 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL6908656 | 0.80 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL1586346 | 0.79 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL1586440 | 0.78 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL6909876 | 0.77 | HCRTR1 (0.55) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050202-A1 | FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-04-28 | — | — | WO | disclosed |