Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 18/20 | 0.55 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668293 | 0.83 | CRACR2A (0.55) | CRACR2AORAI1 | |
| SCHEMBL20006241 | 0.82 | CRACR2A (0.64) | CRACR2AORAI1 | |
| SCHEMBL1667856 | 0.78 | CRACR2A (0.53) | CRACR2AORAI1 | |
| SCHEMBL1876778 | 0.73 | CRACR2A (0.78) | CRACR2AORAI1 | |
| SCHEMBL6888028 | 0.72 | CRACR2A (0.72) | CRACR2AORAI1 | |
| SCHEMBL1671515 | 0.71 | CRACR2A (1.00) | CRACR2AORAI1 | |
| SCHEMBL1882323 | 0.71 | CRACR2A (0.80) | CRACR2AORAI1 | |
| SCHEMBL1669026 | 0.71 | CRACR2A (0.46) | CRACR2AORAI1 | |
| SCHEMBL1669027 | 0.71 | CRACR2A (0.71) | CRACR2AORAI1 | |
| SCHEMBL1668487 | 0.71 | CRACR2A (1.00) | CRACR2AORAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042798-A1 | PYRAZOLES DERIVATIVES MODULATORS OF CALCIUM RELEASE -ACTIVATED CALCIUM CHANNEL AND METHODS FOR TREATMENT OF NON- SMALL CELL LUNG CANCER | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-04-14 | — | — | WO | disclosed |