Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.57 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 2/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | DTYMK | P23919 | 2/20 | 0.45 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065756 | 0.87 | TYMP (0.71) | TYMPPOLBENPP1P2RY1ADORA1 | |
| SCHEMBL7065752 | 0.87 | TYMP (0.71) | TYMPPOLBENPP1P2RY1ADORA1 | |
| SCHEMBL1774839 | 0.81 | TYMP (0.63) | TYMPPOLBENPP1P2RY1ADORA1 | |
| SCHEMBL1774838 | 0.81 | TYMP (0.63) | TYMPPOLBENPP1P2RY1ADORA1 | |
| SCHEMBL29529385 | 0.81 | TYMP (0.63) | TYMPPOLBENPP1P2RY1ADORA1 | |
| SCHEMBL7871248 | 0.81 | TYMP (0.63) | TYMPPOLBENPP1P2RY1ADORA1 | |
| SCHEMBL29574745 | 0.81 | TYMP (0.63) | TYMPPOLBENPP1P2RY1ADORA1 | |
| SCHEMBL888141 | 0.79 | ENPP1 (0.58) | TYMPPOLBENPP1P2RY1ADORA1 | |
| SCHEMBL338780 | 0.79 | POLB (0.60) | TYMPPOLBENPP1P2RY1 | |
| SCHEMBL1140505 | 0.79 | POLB (0.60) | TYMPPOLBENPP1P2RY1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866071-B1 | Modified primers | HOFFMANN LA ROCHE (CH) | 2004-10-20 | — | — | EP | disclosed |
| US-6001611-A | OLIGONUCLEOTIDE PRIMER WITH NUCLEOTIDE TOWARDS THE 3' TERMINAL MODIFIED BY ADDITION OF GROUP ONTO EXOCYCLIC AMINE; RESULTS IN LESS NON-SPECIFIC PRODUCT, PARTICULARLY, PRIMER DIMER, AND A GREATER YIELD | ROCHE MOLECULAR SYSTEMS, INC. (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0866071-A2 | Modified primers | F. HOFFMANN-LA ROCHE AG (CH) | 1998-09-23 | — | — | EP | disclosed |