SCHEMBL6911298

SCHEMBL6911298

COCCNc1ccc(Nc2cc(-c3ccc4cn[nH]c4c3)cn3ccnc23)nc1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SYK P43405 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2426025 0.85 SYK (1.00) SYK
SCHEMBL2428973 0.79 SYK (1.00) SYK
SCHEMBL6911019 0.79 SYK (1.00) SYK
SCHEMBL2426559 0.79 SYK (1.00) SYK
SCHEMBL2431323 0.78 SYK (0.75) SYK
SCHEMBL2427963 0.78 SYK (0.72) SYK
SCHEMBL16224271 0.78 SYK (0.69) SYK
SCHEMBL2426898 0.78 SYK (1.00) SYK
SCHEMBL17095057 0.78 SYK (0.58) SYK
SCHEMBL2405284 0.77 SYK (1.00) SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011112995-A1 IMIDAZOPYRIDINES SYK INHIBITORS GILEAD SCIENCES, INC. (US) 2011-09-15 WO disclosed