Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240702 | 1.00 | TSHR (0.47) | TSHRHPGDTDP1PLA2G2CTHRB | |
| SCHEMBL11251293 | 1.00 | TSHR (0.47) | TSHRHPGDTDP1PLA2G2CTHRB | |
| SCHEMBL11759841 | 0.96 | TSHR (0.42) | TSHRHPGDTDP1PLA2G2CLPAR1 | |
| SCHEMBL6423789 | 0.94 | TSHR (0.53) | TSHRHPGDTDP1PLA2G2CTHRB | |
| SCHEMBL11241729 | 0.91 | TDP1 (0.53) | TSHRHPGDTDP1PLA2G2CTHRB | |
| SCHEMBL11250054 | 0.91 | TDP1 (0.53) | TSHRHPGDTDP1PLA2G2CTHRB | |
| SCHEMBL6909205 | 0.91 | TDP1 (0.53) | TSHRHPGDTDP1PLA2G2CTHRB | |
| SCHEMBL1233877 | 0.87 | TSHR (0.46) | TSHRHPGDTDP1THRBATM | |
| SCHEMBL4904681 | 0.86 | TSHR (0.46) | TSHRHPGDTDP1THRBALDH1A1 | |
| SCHEMBL8850981 | 0.84 | TSHR (0.42) | TSHRHPGDTDP1THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735076-B1 | Process for the production of star-like or comb-like branched aliphatic polyamino compound and curable resin composition | TOYO INK MFG CO (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-5705602-A | Process for the production of star-like or comb-like branched aliphatic polyamino compound and curable resin composition | TOYO INK MANUFACTURING CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0735076-A1 | Process for the production of star-like or comb-like branched aliphatic polyamino compound and curable resin composition | TOYO INK MANUFACTURING CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-4310397-A | SUSTAINED RELEASE; PREPARED BY IRRADIATION POLYMERIZATION | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) | 1982-01-12 | — | — | US | disclosed |