Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 11/20 | 0.40 |
| ▸ | GAA | P10253 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911554 | 1.00 | GFER (0.42) | GFERMAPTGAAALDH1A1RECQL | |
| SCHEMBL5611072 | 0.94 | GFER (0.47) | GFERMAPTGAAALDH1A1MAPK1 | |
| SCHEMBL14586907 | 0.94 | GFER (0.47) | GFERMAPTGAAALDH1A1MAPK1 | |
| SCHEMBL5611068 | 0.94 | GFER (0.47) | GFERMAPTGAAALDH1A1MAPK1 | |
| SCHEMBL181606 | 0.77 | GAA (0.54) | MAPTGAAALDH1A1RECQLMAPK1 | |
| SCHEMBL11400791 | 0.65 | SMN1; SMN2 (0.46) | MAPTGAAALDH1A1RECQLHSD17B10 | |
| SCHEMBL5611084 | 0.65 | NPC1 (0.42) | GFERMAPTALDH1A1MAPK1KMT2A | |
| SCHEMBL14586877 | 0.65 | NPC1 (0.42) | GFERMAPTALDH1A1MAPK1KMT2A | |
| SCHEMBL5611082 | 0.65 | NPC1 (0.42) | GFERMAPTALDH1A1MAPK1KMT2A | |
| SCHEMBL16735374 | 0.64 | SMN1; SMN2 (0.51) | MAPTGAAALDH1A1RECQLMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014852-A2 | IMINOTHIAZOLIDINONES AS INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |
| WO-2004014313-A2 | COMBINATION PHARMACEUTICAL AGENTS AS INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |