Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232582 | 0.90 | TSHR (0.65) | TSHRTDP1L3MBTL1ATMMAPK1 | |
| SCHEMBL234756 | 0.89 | HPGD (0.42) | TSHRATMALDH1A1LMNATHRB | |
| SCHEMBL4628160 | 0.87 | TSHR (0.54) | TSHRTDP1L3MBTL1ATMMAPK1 | |
| SCHEMBL4627304 | 0.86 | TSHR (0.49) | TSHRMAPK1ALDH1A1LMNAHPGD | |
| SCHEMBL4626905 | 0.86 | ESR1 (0.52) | TSHRTDP1L3MBTL1ATMMAPK1 | |
| SCHEMBL4628527 | 0.86 | ATM (0.60) | TSHRTDP1L3MBTL1ATMMAPK1 | |
| SCHEMBL28366858 | 0.86 | TSHR (0.66) | TSHRTDP1L3MBTL1ATMMAPK1 | |
| SCHEMBL4626906 | 0.85 | TSHR (0.55) | TSHRTDP1L3MBTL1ATMMAPK1 | |
| SCHEMBL4628503 | 0.85 | TSHR (0.55) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL4626673 | 0.85 | TSHR (0.67) | TSHRTDP1L3MBTL1ATMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770586-B2 | Solid catalyst component and catalyst for olefins polymerization | TOHO TITANIUM CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |