Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQLE | Q14534 | 20/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911905 | 1.00 | SQLE (0.50) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| SCHEMBL6910987 | 0.89 | SQLE (0.52) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| SCHEMBL6907052 | 0.89 | SQLE (0.52) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| SCHEMBL6907049 | 0.89 | SQLE (0.52) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| SCHEMBL6910572 | 0.87 | SQLE (0.50) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| SCHEMBL6910568 | 0.87 | SQLE (0.50) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL6905711 | 0.86 | SQLE (0.49) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL6905708 | 0.86 | SQLE (0.49) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| SCHEMBL6912002 | 0.84 | SQLE (0.52) | SQLELMNAADRA2ACYP2D6SLC6A2 | |
| SCHEMBL6911234 | 0.84 | SQLE (0.52) | SQLELMNAADRA2ACYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112998-B1 | AMINE DERIVATIVES | POLA CHEM IND INC (JP) | 2004-12-08 | — | — | EP | disclosed |
| US-6586633-B1 | Antifungal agents | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1112998-A1 | AMINE DERIVATIVES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-07-04 | — | — | EP | disclosed |