Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250600 | 0.98 | CYP3A4 (0.54) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL6709164 | 0.81 | LPAR3 (0.55) | CYP3A4LPAR3LPAR2LPAR1LMNA | |
| SCHEMBL56777 | 0.80 | CYP3A4 (0.84) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL29208266 | 0.78 | CYP3A4 (0.59) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL258318 | 0.78 | CYP3A4 (0.80) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL21440331 | 0.78 | CYP3A4 (0.80) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL8040341 | 0.78 | CYP3A4 (0.80) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL21437266 | 0.78 | CYP3A4 (0.80) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL20483847 | 0.78 | CYP3A4 (0.80) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL22230793 | 0.78 | CYP3A4 (0.80) | CYP3A4LPAR3LPAR2LPAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998930-B1 | AZASTEROID COMPOUND FOR TREATING ALOPECIA, HIRSUTISM AND SEBORRHEA | SANKYO CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6380179-B1 | ADMINISTERING N-(1-METHYL-1-(4-METHOXYPHENYL)ETHYL)-3-OXO-4-AZA-5ALPHA-ANDRO ST-1-ENE-17BETA-CARBAXAMIDE | SANKYO COMPANY, LIMITED (JP) | 2002-04-30 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |
| EP-0998930-A1 | REMEDIAL AGENT FOR BALDNESS AND OTHER DISEASES | Sankyo Company Limited (JP) | 2000-05-10 | — | — | EP | disclosed |