Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cefpodoxime. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 1.00 |
| ▸ | HTR2C | P28335 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 0.87 |
| ▸ | PPARG | P37231 | 2/20 | 0.87 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.87 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.87 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.87 |
| ▸ | ALB | P02768 | 1/20 | 0.87 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.75 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.75 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.74 |
| ▸ | APEX1 | P27695 | 3/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefpodoxime SCHEMBL2015784 | 1.00 | NR1I2 (1.00) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefpodoxime SCHEMBL16072818 | 1.00 | NR1I2 (1.00) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefpodoxime SCHEMBL6688590 | 1.00 | NR1I2 (1.00) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefpodoxime SCHEMBL13189562 | 1.00 | NR1I2 (1.00) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefpodoxime SCHEMBL27072 | 1.00 | NR1I2 (1.00) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefpodoxime SCHEMBL2015780 | 1.00 | NR1I2 (1.00) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefpodoxime SCHEMBL3014534 | 0.99 | NR1I2 (0.98) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefpodoxime SCHEMBL8868198 | 0.99 | NR1I2 (0.98) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefpodoxime SCHEMBL6238484 | 0.99 | NR1I2 (0.98) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Cefpodoxime SCHEMBL5265715 | 0.99 | NR1I2 (0.98) | NR1I2HTR2CMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 17435 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637481-B2 | Boronic acid derivatives and therapeutic uses thereof | QPEX BIOPHARMA, INC. (US) | 2026-05-26 | — | — | US | claimed |
| WO-2026104587-A1 | CYCLIC BORONIC ACID ESTERS USEFUL AS ADJUVANTS IN THE TREATMENT OF BACTERIAL INFECTIONS | ADJUTEC PHARMA AS (NO) | 2026-05-21 | — | — | WO | claimed |
| CN-115215923-B | Macrocyclic broad-spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | claimed |
| EP-4739326-A2 | PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA | SNIPR Biome ApS (DK) | 2026-05-13 | — | — | EP | claimed |
| US-12622919-B2 | Methods for treating hypervirulent Klebsiella pneumoniae infection | CITY UNIVERSITY OF HONG KONG (CN) | 2026-05-12 | — | — | US | claimed |
| US-20260115234-A1 | PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA | SNIPR BIOME APS (DK) | 2026-04-30 | — | — | US | claimed |
| US-20260108619-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2026-04-23 | — | — | US | claimed |
| US-12590108-B2 | Boracic acid compound | PHAENO THERAPEUTICS CO., LTD (CN) | 2026-03-31 | — | — | US | claimed |
| EP-4712973-A1 | THERAPY | Adjutec Pharma AS (NO) | 2026-03-25 | — | — | EP | claimed |
| US-12576124-B2 | Formulation of a conjugate of a tubulysin analog to a cell-binding molecule | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2026-03-17 | — | — | US | claimed |
| WO-1998025953-A1 | ANTIMICROBIAL CATIONIC PEPTIDES | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1998-06-18 | — | — | WO | claimed |
| WO-1998025621-A1 | IMPROVED PHARMACEUTICAL COMPOSITIONS | PHARMACIA & UPJOHN COMPANY (US) | 1998-06-18 | — | — | WO | claimed |
| WO-1998022091-A1 | PHARMACEUTICAL PREPARATIONS FOR THE CONTROLLED RELEASE OF β-LACTAM ANTIBIOTICS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1998-05-28 | — | — | WO | claimed |
| WO-1998007745-A9 | COMPOSITIONS AND METHODS FOR TREATING INFECTIONS USING ANALOGUES OF INDOLICIDIN | — | 1998-04-23 | — | — | WO | claimed |
| WO-1998007745-A2 | COMPOSITIONS AND METHODS FOR TREATING INFECTIONS USING ANALOGUES OF INDOLICIDIN | MICROLOGIX BIOTECH, INC. (CA) | 1998-02-26 | — | — | WO | claimed |
| EP-0809708-A1 | POTENTIATORS OF ANTIBACTERIAL AGENTS | Microcide Pharmaceuticals, Inc. (US) | 1997-12-03 | — | — | EP | claimed |
| WO-1997042954-A1 | TOPICAL ADMINISTRATION OF ANTIMICROBIAL AGENTS FOR THE TREATMENT OF SYSTEMIC BACTERIAL DISEASES | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-20 | — | — | WO | claimed |
| WO-1997029765-A1 | ANTIMICROBIAL PEPTIDES AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-08-21 | — | — | WO | claimed |
| WO-1996024684-A1 | POTENTIATORS OF ANTIBACTERIAL AGENTS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1996-08-15 | — | — | WO | claimed |
| US-5198419-A | Lactoferrin | IMMUNO JAPAN INC. (JP) | 1993-03-30 | — | — | US | claimed |