⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26801029 | 0.76 | — | — | |
| SCHEMBL16230148 | 0.74 | — | — | |
| SCHEMBL20860751 | 0.72 | — | — | |
| SCHEMBL13981305 | 0.72 | — | — | |
| SCHEMBL19956125 | 0.70 | — | — | |
| SCHEMBL22386210 | 0.70 | — | — | |
| SCHEMBL22838129 | 0.70 | — | — | |
| SCHEMBL14242115 | 0.70 | — | — | |
| SCHEMBL24404184 | 0.67 | — | — | |
| SCHEMBL21670002 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011046771-A1 | SUBSTITUTED PIPERIDINES THAT INCREASE p53 ACTIVITY AND THE USES THEREOF | SCHERING CORPORATION (US) | 2011-04-21 | — | — | WO | disclosed |