Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789870 | 0.90 | TSHR (0.48) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL1764285 | 0.81 | TSHR (0.41) | TSHRHPGD | |
| SCHEMBL14574685 | 0.77 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL877669 | 0.77 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL4458184 | 0.77 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL7730973 | 0.77 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL7647533 | 0.77 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL21218910 | 0.77 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL22607678 | 0.77 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL14967 | 0.77 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831131-B2 | Comprises 1-40% by weight of impact modifier comprising ethylene/acrylate copolymers, vinyl acetate copolymers, polyethylene obtained by metallocene catalysis | ATOFINA (FR) | 2004-12-14 | — | — | US | claimed |
| US-20030130429-A1 | Composition based on polypropylene on an ethylene/alkyl acrylate copolymer | ATOFINA (FR) | 2003-07-10 | — | — | US | claimed |