SCHEMBL6913578

SCHEMBL6913578

CCOC(=O)CCc1ccc(F)c(F)c1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.61
CYP4A11 Q02928 2/20 0.61
ALDH1A1 P00352 2/20 0.51
CYP4Z1 Q86W10 2/20 0.49
PDE3B Q13370 1/20 0.47
PDE3A Q14432 1/20 0.47
P2RY12 Q9H244 1/20 0.47
APP P05067 2/20 0.46
EPHX2 P34913 1/20 0.43
HRH3 Q9Y5N1 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
RIPK1 Q13546 1/20 0.41
CYP4F11 Q9HBI6 1/20 0.41
CYP4F12 Q9HCS2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8257852 0.89 CYP4F2 (0.59) CYP4F2CYP4A11ALDH1A1CYP4Z1PDE3B
SCHEMBL8364365 0.89 CYP4F2 (0.59) CYP4F2CYP4A11ALDH1A1CYP4Z1PDE3B
SCHEMBL2347025 0.88 CYP4F2 (0.58) CYP4F2CYP4A11CYP4Z1PDE3BPDE3A
SCHEMBL6985238 0.88 CYP4F2 (0.58) CYP4F2CYP4A11ALDH1A1CYP4Z1PDE3B
SCHEMBL12984627 0.86 CYP4F2 (0.56) CYP4F2CYP4A11ALDH1A1CYP4Z1PDE3B
SCHEMBL7520208 0.86 CYP4F2 (0.56) CYP4F2CYP4A11CYP4Z1PDE3BPDE3A
SCHEMBL11247614 0.86 CYP4F2 (0.56) CYP4F2CYP4A11ALDH1A1CYP4Z1PDE3B
SCHEMBL901163 0.86 CYP4F2 (0.56) CYP4F2CYP4A11ALDH1A1CYP4Z1PDE3B
SCHEMBL901787 0.86 CYP4F2 (0.56) CYP4F2CYP4A11ALDH1A1CYP4Z1PDE3B
Hydrochloric Acid SCHEMBL6982842 0.86 CYP4F2 (0.56) CYP4F2CYP4A11ALDH1A1CYP4Z1PDE3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015088564-A1 P2X4 RECEPTOR MODULATING COMPOUNDS SUNOVION PHARMACEUTICALS INC. (US) 2015-06-18 WO disclosed
WO-2015088564-A1 P2X4 RECEPTOR MODULATING COMPOUNDS SUNOVION PHARMACEUTICALS INC. (US) 2015-06-18 WO disclosed
CN-1572782-A Process for the preparation of fluorophenylalkylene acid derivatives DAINIPPON INK & CHEMICALS (JP) 2005-02-02 CN disclosed
EP-1484304-A1 Process for the preparation of fluorophenylalkylene acid derivatives DAINIPPON INK AND CHEMICALS, INC. (JP) 2004-12-08 EP disclosed