Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6913681 | 1.00 | GRM2 (0.37) | GRM2GRM3KMT2AMEN1CYP2C19 | |
| SCHEMBL6911129 | 0.94 | GRM2 (0.38) | GRM2GRM3KMT2AMEN1ALDH1A1 | |
| SCHEMBL6911124 | 0.94 | GRM2 (0.38) | GRM2GRM3KMT2AMEN1ALDH1A1 | |
| SCHEMBL6906612 | 0.93 | GRM2 (0.43) | GRM2GRM3TSHRHDAC4HDAC6 | |
| SCHEMBL6906608 | 0.93 | GRM2 (0.43) | GRM2GRM3TSHRHDAC4HDAC6 | |
| SCHEMBL6904297 | 0.93 | GRM2 (0.43) | GRM2GRM3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6904292 | 0.93 | GRM2 (0.43) | GRM2GRM3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6909757 | 0.92 | GRM2 (0.47) | GRM2GRM3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6909754 | 0.92 | GRM2 (0.47) | GRM2GRM3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6909913 | 0.91 | USP30 (0.44) | GRM2GRM3KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |