Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 17/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL908462 | 1.00 | CYP19A1 (0.46) | CYP19A1PGRARNR3C2 | |
| SCHEMBL13804522 | 1.00 | CYP19A1 (0.46) | CYP19A1PGRARNR3C2 | |
| SCHEMBL6840974 | 0.87 | CYP19A1 (0.47) | CYP19A1PGRARNR3C2 | |
| SCHEMBL4587495 | 0.81 | CYP19A1 (0.44) | CYP19A1PGRARNR3C2 | |
| SCHEMBL1656805 | 0.78 | AR (0.58) | CYP19A1PGRARNR3C2 | |
| SCHEMBL13809834 | 0.78 | AR (0.58) | CYP19A1PGRARNR3C2 | |
| SCHEMBL12902157 | 0.74 | CYP19A1 (0.64) | CYP19A1PGR | |
| SCHEMBL908750 | 0.74 | CYP19A1 (0.64) | CYP19A1PGR | |
| SCHEMBL4588011 | 0.73 | CYP19A1 (0.49) | CYP19A1PGRARNR3C2 | |
| SCHEMBL13804516 | 0.73 | CYP19A1 (0.49) | CYP19A1PGRARNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677324-B1 | MIXTURE INCLUDES 7A-(E-AMINOALKYL)-ESTRATRIENE; HORMONE REPLACEMENT THERAPY; MENOPAUSE | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-01-13 | — | — | US | disclosed |