Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.50 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.48 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31277112 | 0.75 | KCNJ5 (0.50) | NPC1RAB9ANR2E1KCNJ5KCNJ3 | |
| SCHEMBL26789810 | 0.75 | TSHR (0.53) | SMN1; SMN2CYP1A2CYP2C19CYP3A4RECQL | |
| SCHEMBL4215163 | 0.73 | NPC1 (0.54) | NPC1RAB9ANR2E1KCNJ5KCNJ3 | |
| SCHEMBL12284882 | 0.73 | KCNJ5 (0.53) | NPC1RAB9AHTTKCNJ5KCNJ3 | |
| SCHEMBL30794694 | 0.70 | MAPT (0.50) | NPC1RAB9ASMN1; SMN2HTTKCNJ5 | |
| SCHEMBL2438404 | 0.70 | MAPT (0.50) | NPC1RAB9ASMN1; SMN2HTTKCNJ5 | |
| SCHEMBL6393799 | 0.70 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2CYP2C19CYP3A4 | |
| SCHEMBL10989847 | 0.69 | ANO1 (0.57) | NPC1RAB9ASMN1; SMN2CYP2C19CYP3A4 | |
| SCHEMBL30502369 | 0.69 | KCNJ5 (0.68) | NPC1RAB9ASMN1; SMN2CYP3A4KCNJ5 | |
| SCHEMBL96174 | 0.69 | KCNJ5 (0.68) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043904-A1 | N-(4-pyrazolyl) amide derivatives, chemicals for agricultural and horticultural use, and usage of the same | NIHON NOHYAKU CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-1319657-A1 | N-(4-PYRAZOLYL)AMIDE DERIVATIVES, CHEMICALS FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE OF THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2003-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043904-A1 | N-(4-pyrazolyl) amide derivatives, chemicals for agricultural and horticultural use, and usage of the same | CBR3, CYP8B1, CBR1 | NPC1 1234/4885RAB9A 3798/4885SMN1; SMN2 4324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.