Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 14/20 | 0.41 |
| ▸ | CTRC | Q99895 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6913295 | 0.93 | CMA1 (0.41) | F2PRSS1CMA1CTRCITGB3 | |
| SCHEMBL6914206 | 0.90 | CMA1 (0.41) | F2PRSS1CMA1CTRCITGB3 | |
| SCHEMBL6914255 | 0.90 | CMA1 (0.41) | F2PRSS1CMA1CTRCITGB3 | |
| SCHEMBL6913735 | 0.84 | F2 (0.41) | F2PRSS1CMA1CTRC | |
| SCHEMBL6885026 | 0.79 | CMA1 (0.41) | F2PRSS1CMA1CTRCITGB3 | |
| SCHEMBL8037240 | 0.78 | F2 (0.46) | F2PRSS1CMA1CTRCITGB3 | |
| SCHEMBL6914145 | 0.78 | F2 (0.46) | F2PRSS1CMA1CTRCITGB3 | |
| SCHEMBL8221022 | 0.76 | PRCP (0.36) | F2PRSS1ACE | |
| SCHEMBL15178618 | 0.74 | CYP3A4 (0.43) | — | |
| SCHEMBL6913290 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002807-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2011-01-06 | — | — | WO | disclosed |
| WO-2009082697-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2009-07-02 | — | — | WO | disclosed |