Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 4/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808681 | 0.92 | PPARG (0.43) | PPARGCYSLTR2CYSLTR1PRSS1PRSS2 | |
| SCHEMBL9808676 | 0.89 | PPARG (0.39) | PPARGCYSLTR2CYSLTR1PRSS1PRSS2 | |
| SCHEMBL9791219 | 0.84 | PPARG (0.46) | PPARGCYSLTR2CYSLTR1CETPFDPS | |
| SCHEMBL7515998 | 0.82 | PPARG (0.44) | PPARGCYSLTR2CYSLTR1CETPFDPS | |
| SCHEMBL4530208 | 0.82 | PPARG (0.44) | PPARGCYSLTR2CYSLTR1CETPFDPS | |
| SCHEMBL7784135 | 0.81 | PPARG (0.40) | PPARGCYSLTR2CYSLTR1PRSS1PRSS2 | |
| SCHEMBL4453788 | 0.80 | INPPL1 (0.40) | PPARGCYSLTR2CYSLTR1FDPSSMPD1 | |
| SCHEMBL29028928 | 0.79 | PPARG (0.42) | PPARGCYSLTR2CYSLTR1PRSS1PRSS2 | |
| SCHEMBL11970231 | 0.79 | PPARG (0.46) | PPARGCYSLTR2CYSLTR1PRSS1PRSS2 | |
| SCHEMBL7515994 | 0.79 | CYSLTR2 (0.42) | PPARGCYSLTR2CYSLTR1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185586-B1 | COMPOSITIONS WITH ENHANCED DUCTILITY | GEN ELECTRIC (US) | 2004-12-15 | — | — | EP | claimed |