⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618370 | 0.86 | — | — | |
| SCHEMBL1008111 | 0.63 | — | — | |
| SCHEMBL16241619 | 0.56 | — | — | |
| SCHEMBL6277862 | 0.54 | — | — | |
| SCHEMBL11353484 | 0.54 | — | — | |
| SCHEMBL1929781 | 0.54 | — | — | |
| SCHEMBL737627 | 0.51 | — | — | |
| SCHEMBL7954 | 0.50 | — | — | |
| SCHEMBL5760574 | 0.49 | — | — | |
| SCHEMBL135915 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125484-A | Tertiary alcohols | SHELL OIL COMPANY (US) | 1978-11-14 | — | — | US | claimed |
| US-20240238438-A1 | CD-90 Targeted Lipid Nanoparticles | FRED HUTCHINSON CANCER CENTER | 2024-07-18 | — | — | US | disclosed |
| US-20240226310-A1 | Lipid Nanoparticle Therapeutics that Evade the Immune Response | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2024-07-11 | — | — | US | disclosed |
| US-20240216523-A1 | Compositions and Methods for Targeting Lipid Nanoparticle Therapeutics to Stem Cells | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-07-04 | — | — | US | disclosed |
| WO-2024137663-A2 | TREATMENT OF DKK2 RELATED DISEASES AND DISORDERS | EMPIRICO INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| US-12012395-B2 | Pyridazinone compounds and uses thereof | EDGEWISE THERAPEUTICS, INC. (US) | 2024-06-18 | — | — | US | disclosed |
| WO-2024124143-A2 | HSC TARGETED LNP FOR DELIVERY OF PRO-APOPTOTIC MRNA AND METHODS OF USE THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2024-06-13 | — | — | WO | disclosed |
| US-20240189445-A1 | Targeted Therapeutic Lipid Nanoparticles and Methods of Use | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-06-13 | — | — | US | disclosed |
| WO-2024118979-A1 | TREATMENT OF MTRES1 RELATED DISEASES AND DISORDERS | EMPIRICO INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| US-20240175023-A1 | GALNAC COMPOSITIONS FOR IMPROVING SIRNA BIOAVAILABILITY | EMPIRICO INC. | 2024-05-30 | — | — | US | disclosed |
| WO-2011116161-A2 | ARYLSULFONAMIDE CCR3 ANTAGONISTS | AXIKIN PHARMACEUTICALS INC. (US) | 2011-09-22 | — | — | WO | disclosed |
| US-20110230487-A1 | ARYLSULFONAMIDE CCR3 ANTAGONISTS | AXIKIN PHARMACEUTICALS, INC. | 2011-09-22 | — | — | US | disclosed |
| WO-2011109345-A1 | ISOTOPICALLY ENRICHED ARYLSULFONAMIDE CCR3 ANTAGONISTS | AXIKIN PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |
| US-20110218207-A1 | ISOTOPICALLY ENRICHED ARYLSULFONAMIDE CCR3 ANTAGONISTS | AXIKIN PHARMACEUTICALS, INC. (US) | 2011-09-08 | — | — | US | disclosed |
| EP-2265611-A1 | TRICYCLIC DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. (IT) | 2010-12-29 | — | — | EP | disclosed |
| US-20100273795-A1 | ARYLSULFONAMIDE CCR3 ANTAGONISTS | AXIKIN PHARMACEUTICALS, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| WO-2010123960-A2 | ARYLSULFONAMIDE CCR3 ANTAGONISTS | AXIKIN PHARMACEUTICALS, INC. (US) | 2010-10-28 | — | — | WO | disclosed |
| WO-2009112832-A1 | TRICYCLIC DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2009-09-17 | — | — | WO | disclosed |
| EP-0379110-A2 | Silver halide color photographic light-sensitive material | KONICA CORPORATION (JP) | 1990-07-25 | — | — | EP | disclosed |
| US-4125484-A | Tertiary alcohols | SHELL OIL COMPANY (US) | 1978-11-14 | — | — | US | disclosed |