Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919562 | 0.86 | SCN9A (0.36) | F2KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL6077624 | 0.86 | F2 (0.47) | F2 | |
| SCHEMBL6921204 | 0.83 | F2 (0.40) | F2KMT2AMEN1L3MBTL1AAK1 | |
| Hydrochloric Acid SCHEMBL6919401 | 0.81 | F2 (0.41) | F2KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL6915417 | 0.80 | F2 (0.49) | F2 | |
| SCHEMBL6915431 | 0.80 | F2 (0.49) | F2 | |
| SCHEMBL6078268 | 0.76 | F2 (0.45) | F2 | |
| SCHEMBL6077401 | 0.75 | F2 (0.48) | F2KMT2AMEN1 | |
| SCHEMBL6921239 | 0.73 | F2 (0.38) | F2KMT2AMEN1L3MBTL1AAK1 | |
| SCHEMBL6077615 | 0.73 | F2 (0.60) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004032834-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2004-04-22 | — | — | WO | claimed |
| WO-2004032834-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2004-04-22 | — | — | WO | disclosed |