Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 14/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7613616 | 0.94 | CHRM1 (0.60) | CHRM4CHRM1 | |
| SCHEMBL7611914 | 0.86 | CHRM4 (0.63) | CHRM4CHRM1CHRM2CHRM5CHRM3 | |
| SCHEMBL6914130 | 0.83 | CHRM4 (0.69) | CHRM4CHRM1CHRM2CHRM5CHRM3 | |
| SCHEMBL6915575 | 0.82 | CHRM4 (0.67) | CHRM4CHRM1CHRM2CHRM5CHRM3 | |
| Oxalic Acid SCHEMBL7618917 | 0.80 | CHRM1 (0.61) | CHRM4CHRM1 | |
| SCHEMBL6915833 | 0.80 | CHRM4 (0.72) | CHRM4CHRM1CHRM2CHRM5CHRM3 | |
| SCHEMBL6912866 | 0.80 | CHRM4 (0.76) | CHRM4CHRM1CHRM2CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL7900558 | 0.79 | CHRM4 (0.67) | CHRM4CHRM1CHRM2CHRM5CHRM3 | |
| SCHEMBL6915126 | 0.79 | CHRM4 (0.63) | CHRM4CHRM1CHRM2CHRM5CHRM3 | |
| SCHEMBL7611092 | 0.79 | CHRM4 (0.63) | CHRM4CHRM1CHRM2CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734259-B1 | Use of piperidine compounds in the treatment of schizophrenia | NOVO NORDISK AS (DK) | 2002-06-12 | — | — | EP | claimed |
| US-5753683-A | SCHIZOPHRENIA | NOVO NORDISK A/S (DK) | 1998-05-19 | — | — | US | claimed |
| US-5744489-A | ADMINISTERING CERTAIN 1,2,5-THIADIAZOLE AND 1,2,5-OXADIAZOLE COMPOUNDS | GREENWOOD BEVERLEY (US) | 1998-04-28 | — | — | US | claimed |
| US-20040023951-A1 | Combination therapy for treatment of psychoses | ELI LILLY AND COMPANY | 2004-02-05 | — | — | US | disclosed |
| EP-1316203-A2 | COMBINATION FOR TREATING PSYCHOSES, COMPRISING AN ANTIPSYCHOTIC AND A MUSCARINIC AGONIST | ELI LILLY AND COMPANY (US) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002003684-A2 | COMBINATION FOR TREATING PSYCHOSES, COMPRISING AN ANTIPSYCHOTIC AND A MUSCARINIC AGONIST | ELI LILLY AND COMPANY (US) | 2002-01-10 | — | — | WO | disclosed |
| EP-0709094-B1 | Tetrahydropyridine oxadiazole or thiadiazole compound for treating anxiety | LILLY CO ELI (US) | 2000-04-05 | — | — | EP | disclosed |
| US-5708014-A | SUBSTITUTED TETRAHYDROPYRIDINYL-1,2,5-OXADIAZOLES OR THIADIAZOLES | ELI LILLY AND COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0709094-A2 | Method for treating anxiety using a tetrahydropyridine oxadiazole or thiadiazole compound | ELI LILLY AND COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023951-A1 | Combination therapy for treatment of psychoses | CHRM5, CHRM4, CHRM2 | CHRM4 2/4885CHRM1 8/4885CHRM2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.