Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2372991 | 0.90 | PDE10A (0.59) | PDE10A | |
| SCHEMBL2388072 | 0.90 | PDE10A (0.64) | PDE10A | |
| SCHEMBL2373185 | 0.89 | PDE10A (0.59) | PDE10A | |
| SCHEMBL2373577 | 0.89 | PDE10A (0.59) | PDE10A | |
| SCHEMBL2395216 | 0.89 | PDE10A (0.59) | PDE10A | |
| SCHEMBL2386273 | 0.89 | PDE10A (0.71) | PDE10A | |
| SCHEMBL2374141 | 0.88 | PDE10A (0.64) | PDE10A | |
| SCHEMBL2373782 | 0.88 | PDE10A (0.56) | PDE10A | |
| SCHEMBL2385835 | 0.87 | PDE10A (0.71) | PDE10A | |
| SCHEMBL2373581 | 0.86 | PDE10A (0.70) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011117264-A1 | N-(IMIDAZOPYRIMIDIN-7-YL)-HETEROARYLAMIDE DERIVATIVES AND THEIR USE AS PDE10A INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-09-29 | — | — | WO | disclosed |