Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | DUSP1 | P28562 | 3/20 | 0.61 |
| ▸ | HPSE | Q9Y251 | 6/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL6821818 | 0.99 | MAPT (0.61) | MAPTPOLBDUSP1HPSERXFP1 | |
| SCHEMBL20515146 | 0.86 | HPSE (0.77) | MAPTHPSETP53NPC1USP2 | |
| SCHEMBL6821021 | 0.81 | HPSE (0.65) | MAPTPOLBHPSETP53USP2 | |
| SCHEMBL4055488 | 0.79 | MAPT (0.77) | MAPTPOLBDUSP1RXFP1TP53 | |
| SCHEMBL6821031 | 0.78 | DUSP1 (0.59) | MAPTPOLBDUSP1RXFP1TP53 | |
| SCHEMBL507169 | 0.77 | KDM4E (0.77) | POLBHPSENPC1MAPK1RAB9A | |
| SCHEMBL19410571 | 0.77 | MAPT (0.80) | MAPTPOLBHPSERXFP1TP53 | |
| SCHEMBL28384392 | 0.77 | P2RY14 (0.83) | MAPTPOLBDUSP1RXFP1USP2 | |
| SCHEMBL30153371 | 0.77 | P2RY14 (0.83) | MAPTPOLBDUSP1RXFP1USP2 | |
| SCHEMBL6821359 | 0.75 | HPSE (1.00) | HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |