Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.69 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.51 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914052 | 1.00 | FFAR1 (0.69) | FFAR1GABBR2GABBR1CYP2C9MEN1 | |
| SCHEMBL4249915 | 0.93 | FFAR1 (0.60) | FFAR1GABBR2GABBR1CYP2C9MEN1 | |
| SCHEMBL20902118 | 0.89 | FFAR1 (0.56) | FFAR1GABBR2GABBR1CYP2C9MEN1 | |
| SCHEMBL18603480 | 0.87 | FFAR1 (0.55) | FFAR1GABBR2GABBR1CYP2C9MEN1 | |
| SCHEMBL18603481 | 0.87 | FFAR1 (0.55) | FFAR1GABBR2GABBR1CYP2C9MEN1 | |
| SCHEMBL17086508 | 0.87 | FFAR1 (0.55) | FFAR1GABBR2GABBR1CYP2C9MEN1 | |
| SCHEMBL22088139 | 0.87 | FFAR1 (0.54) | FFAR1GABBR2GABBR1CYP2C9MEN1 | |
| SCHEMBL12836112 | 0.85 | FFAR1 (0.50) | FFAR1GABBR2GABBR1CYP2C9MEN1 | |
| SCHEMBL17761361 | 0.85 | FFAR1 (0.50) | FFAR1GABBR2GABBR1CYP2C9MEN1 | |
| SCHEMBL17761387 | 0.85 | FFAR1 (0.50) | FFAR1GABBR2GABBR1CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770463-B2 | INSECTICIDES AND ACARICIDES; AROMATIC SUBSTITUTED HALOALKENES | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-03 | — | — | US | claimed |
| EP-1307418-A2 | PROCESS FOR THE PREPARATION OF CHIRAL 1,4-DIARYL-2-FLUORO-2-BUTENES | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-07 | — | — | EP | claimed |
| US-20020032351-A1 | Process for the preparation of chiral isofluoroenes | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-14 | — | — | US | claimed |
| WO-2002012155-A2 | PROCESS FOR THE PREPARATION OF CHIRAL 1,4-DIARYL-2-FLUORO-2-BUTENES | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-14 | — | — | WO | claimed |
| US-6770463-B2 | INSECTICIDES AND ACARICIDES; AROMATIC SUBSTITUTED HALOALKENES | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-03 | — | — | US | disclosed |
| EP-1307418-A2 | PROCESS FOR THE PREPARATION OF CHIRAL 1,4-DIARYL-2-FLUORO-2-BUTENES | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-07 | — | — | EP | disclosed |
| US-20020032351-A1 | Process for the preparation of chiral isofluoroenes | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-14 | — | — | US | disclosed |
| WO-2002012155-A2 | PROCESS FOR THE PREPARATION OF CHIRAL 1,4-DIARYL-2-FLUORO-2-BUTENES | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032351-A1 | Process for the preparation of chiral isofluoroenes | CYP51A1, CYP4F11, CYP2F1 | FFAR1 1090/4885GABBR2 3894/4885GABBR1 3743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.