SCHEMBL6916072

SCHEMBL6916072

c1ccc(CSSSSSSSCc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.44
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
MAOB P27338 1/20 0.43
HSD17B10 Q99714 2/20 0.43
POLB P06746 1/20 0.43
CALM1 P0DP23 1/20 0.43
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C19 P33261 2/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11853076 1.00 IDO1 (0.44) IDO1NOS3NOS1NOS2MAOB
SCHEMBL1255808 1.00 IDO1 (0.44) IDO1NOS3NOS1NOS2MAOB
SCHEMBL1255779 0.97 IDO1 (0.46) IDO1NOS3NOS1NOS2MAOB
Dibenzyl Trisulfide SCHEMBL2803113 0.92 IDO1 (0.46) IDO1NOS3NOS1NOS2MAOB
Dibenzyl Disulfide SCHEMBL160895 0.85 HSD17B10 (0.52) IDO1NOS3NOS1NOS2MAOB
Dibenzyl Disulfide SCHEMBL16332737 0.85 HSD17B10 (0.52) IDO1NOS3NOS1NOS2MAOB
Dibenzyl Disulfide SCHEMBL1741790 0.82 IDO1 (0.52) IDO1NOS3NOS1NOS2MAOB
Dibenzyl Disulfide SCHEMBL30254005 0.82 HSD17B10 (0.50) IDO1NOS3NOS1NOS2MAOB
Dibenzyl Disulfide SCHEMBL31120434 0.82 HSD17B10 (0.50) IDO1NOS3NOS1NOS2MAOB
Dibenzyl Disulfide SCHEMBL32679343 0.82 HSD17B10 (0.50) IDO1NOS3NOS1NOS2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed