Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 7/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.42 |
| ▸ | ITGAL | P20701 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308785 | 0.85 | ITGAL (0.44) | ITGB2ICAM1ITGALKMT2AMEN1 | |
| SCHEMBL6312229 | 0.80 | ITGAL (0.49) | ITGB2ICAM1ITGALKMT2AMAPK1 | |
| SCHEMBL6308779 | 0.79 | ITGAL (0.49) | ITGB2ICAM1ITGALKMT2AMEN1 | |
| SCHEMBL6199010 | 0.77 | ITGAL (0.64) | ITGB2ICAM1ITGALKMT2AMEN1 | |
| SCHEMBL6199467 | 0.75 | ITGAL (0.48) | ITGB2ICAM1ITGAL | |
| SCHEMBL6199566 | 0.75 | ITGAL (0.51) | ITGB2ICAM1ITGAL | |
| SCHEMBL6196144 | 0.73 | ITGAL (0.46) | ITGB2ICAM1ITGALKMT2AMEN1 | |
| SCHEMBL6310933 | 0.73 | ITGAL (0.51) | ITGB2ICAM1ITGALSMN1; SMN2 | |
| SCHEMBL6197126 | 0.72 | ITGAL (0.50) | ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL6199827 | 0.71 | ITGAL (0.45) | ITGB2ICAM1ITGALSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |