Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.37 |
| ▸ | CES2 | O00748 | 4/20 | 0.37 |
| ▸ | CES1 | P23141 | 4/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARD | Q03181 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613082 | 0.90 | CYP4F2 (0.38) | MEN1KMT2ASPHK1CES2CES1 | |
| SCHEMBL277833 | 0.90 | CYP4F2 (0.32) | — | |
| SCHEMBL1044919 | 0.88 | CYP4F2 (0.41) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL7197775 | 0.88 | CYP4F2 (0.41) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL5031163 | 0.88 | CYP4F2 (0.41) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL12273347 | 0.88 | CETP (0.36) | SPHK1CES2CES1 | |
| SCHEMBL11579875 | 0.87 | SOAT1 (0.45) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL6153916 | 0.82 | CYP4F2 (0.38) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL5046466 | 0.82 | CYP4F2 (0.34) | CYP2C19 | |
| SCHEMBL277294 | 0.82 | CYP4F2 (0.38) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737464-B1 | MELT PROCESSIBLE; LOW HAZE; IMPROVED OXYGEN BARRIER | UNIVERSITY OF SOUTH CAROLINA RESEARCH FOUNDATION | 2004-05-18 | — | — | US | disclosed |