Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.70 |
| ▸ | HTR2C | P28335 | 1/20 | 0.70 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919591 | 0.88 | MCHR1 (0.62) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6926340 | 0.87 | MCHR1 (0.92) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6927905 | 0.86 | MCHR1 (0.78) | MCHR1HTR2C | |
| SCHEMBL6925891 | 0.86 | MCHR1 (0.78) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6929428 | 0.85 | MCHR1 (0.73) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6570538 | 0.84 | MCHR1 (0.74) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6569784 | 0.84 | MCHR1 (0.74) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6927129 | 0.83 | MCHR1 (0.93) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6924942 | 0.83 | MCHR1 (0.75) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6569788 | 0.83 | MCHR1 (0.73) | MCHR1HTR2CSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011427-A2 | SUBSTITUTED BENZANILIDES AS MODULATORS OF THE CCR5 RECEPTOR | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |