Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.53 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.53 |
| ▸ | POLG | P54098 | 2/20 | 0.49 |
| ▸ | PNP | P00491 | 3/20 | 0.48 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | KRAS | P01116 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806886 | 0.91 | POLB (0.60) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL16503343 | 0.84 | POLB (0.64) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL16509553 | 0.84 | POLB (0.64) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL29546691 | 0.83 | POLB (0.57) | POLBP2RY2P2RY4P2RY6PNP | |
| SCHEMBL28094790 | 0.83 | POLB (0.59) | POLBP2RY2P2RY4P2RY6PNP | |
| SCHEMBL30712246 | 0.82 | POLB (0.58) | POLBP2RY2P2RY4P2RY6PNP | |
| SCHEMBL6909227 | 0.82 | POLB (0.58) | POLBP2RY2 | |
| Deoxyguanosine SCHEMBL3032287 | 0.82 | POLB (0.74) | POLBP2RY2P2RY4P2RY6POLG | |
| Deoxyguanosine Triphosphate SCHEMBL80609 | 0.82 | POLB (0.81) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL16699229 | 0.82 | POLB (0.81) | POLBP2RY2P2RY4P2RY6POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084266-B1 | THE APPLICATION OF 5'-MODIFIED NUCLEOTIDES IN MOLECULAR BIOLOGY AND MEDICINE | EUROP LAB MOLEKULARBIOLOG (DE) | 2004-06-30 | — | — | EP | disclosed |
| US-6627416-B1 | Synthesizing copies of double-stranded nucleic acid from a single-stranded one by enzymatic incorporation of compound of given formula; site-directed cleavage; use for detecting nucleic acids and mutations and for sequencing | EUROPAISCHES LABORATORIUM FUR MOLEKULARBIOLOGIE (EMBL) (DE) | 2003-09-30 | — | — | US | disclosed |
| EP-1084266-A2 | 5'-MODIFIED NUCLEOTIDES AND THE APPLICATION THEREOF IN MOLECULAR BIOLOGY AND MEDICINE | Europäisches Laboratorium für Molekularbiologie (DE) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999053087-A2 | 5'-MODIFIED NUCLEOTIDES AND THE APPLICATION THEREOF IN MOLECULAR BIOLOGY AND MEDICINE | Europäisches Laboratorium für Molekularbiologie (EMBL) (DE) | 1999-10-21 | — | — | WO | disclosed |