Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 14/20 | 0.61 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.58 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26914667 | 0.91 | PTGER4 (0.75) | PTGER4PTGER2 | |
| SCHEMBL1284749 | 0.91 | PTGER4 (0.75) | PTGER4PTGER2 | |
| SCHEMBL4015056 | 0.88 | PTGER4 (0.62) | PTGER4INPPL1PTGER2 | |
| SCHEMBL691681 | 0.86 | PTGER4 (0.63) | PTGER4PTGER2MAPK1GPR139 | |
| SCHEMBL690994 | 0.81 | PTGER4 (0.72) | PTGER4PTGER2 | |
| SCHEMBL692072 | 0.81 | PTGER4 (0.71) | PTGER4PTGER2GPR139 | |
| SCHEMBL26914666 | 0.80 | PTGER4 (0.75) | PTGER4PTGER2 | |
| SCHEMBL1285383 | 0.80 | PTGER4 (0.75) | PTGER4PTGER2 | |
| SCHEMBL4013890 | 0.78 | PTGER4 (0.60) | PTGER4PTGER2MAPK1 | |
| SCHEMBL692450 | 0.78 | PTGER4 (0.68) | PTGER4PTGER2GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2422779-A1 | SELECTIVE EP4 RECEPTOR AGONISTIC SUBSTANCE FOR TREATMENT OF CANCER | RaQualia Pharma Inc (JP) | 2012-02-29 | — | — | EP | claimed |
| EP-3431085-A1 | SELECTIVE EP4 RECEPTOR ANTAGONISTIC SUBSTANCE FOR TREATMENT OF CANCER | AskAt Inc. (JP) | 2019-01-23 | — | — | EP | disclosed |
| EP-2965756-A1 | SELECTIVE EP4 RECEPTOR ANTAGONISTIC SUBSTANCE FOR TREATMENT OF CANCER | RaQualia Pharma Inc (JP) | 2016-01-13 | — | — | EP | disclosed |
| EP-2422779-A1 | SELECTIVE EP4 RECEPTOR AGONISTIC SUBSTANCE FOR TREATMENT OF CANCER | RaQualia Pharma Inc (JP) | 2012-02-29 | — | — | EP | disclosed |