Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 10/20 | 0.76 |
| ▸ | F11 | P03951 | 4/20 | 0.76 |
| ▸ | F7 | P08709 | 4/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | F10 | P00742 | 2/20 | 0.74 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.41 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607691 | 0.88 | F9 (0.67) | F9F11F7CYP2C9F10 | |
| SCHEMBL1233112 | 0.87 | F9 (1.00) | F9F11F7CYP2C9F10 | |
| SCHEMBL8514912 | 0.85 | F9 (0.68) | F9F11F7CYP2C9F10 | |
| SCHEMBL6919026 | 0.85 | F9 (1.00) | F9F11F7CYP2C9F10 | |
| SCHEMBL1232213 | 0.85 | F9 (0.68) | F9F11F7CYP2C9F10 | |
| SCHEMBL1232149 | 0.85 | F9 (1.00) | F9F11F7CYP2C9F10 | |
| SCHEMBL1232214 | 0.85 | F9 (0.68) | F9F11F7CYP2C9F10 | |
| SCHEMBL9607661 | 0.85 | F9 (0.67) | F9F11F7CYP2C9F10 | |
| SCHEMBL1233196 | 0.84 | F9 (0.66) | F9F11F7CYP2C9F10 | |
| SCHEMBL9607697 | 0.84 | F9 (0.66) | F9F11F7CYP2C9F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011017296-A1 | 4, 5, 6-TRISUBSTITUTED PYRIMIDINE DERIVATIVES AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2011-02-10 | — | — | WO | disclosed |