Cinnamic Acid

Cinnamic Acid

SCHEMBL6918830

C1CC[SiH2]OC1.O=C(O)/C=C/c1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.58
HDAC3 O15379 2/20 0.58
HDAC4 P56524 2/20 0.58
HDAC1 Q13547 2/20 0.58
HDAC2 Q92769 2/20 0.58
HDAC8 Q9BY41 2/20 0.58
HDAC6 Q9UBN7 2/20 0.58
TNKS O95271 1/20 0.58
HDAC7 Q8WUI4 1/20 0.58
HDAC10 Q969S8 1/20 0.58
HDAC11 Q96DB2 1/20 0.58
TNKS2 Q9H2K2 1/20 0.58
HDAC9 Q9UKV0 1/20 0.58
HDAC5 Q9UQL6 1/20 0.58
LMNA P02545 4/20 0.44
MAPT P10636 4/20 0.44
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
PLIN1 O60240 2/20 0.44
RECQL P46063 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinnamic Acid SCHEMBL6918836 1.00 HCAR2 (0.58) HCAR2HDAC3HDAC4HDAC1HDAC2
Chalcone SCHEMBL5960624 0.87 MAPT (0.61) HDAC3HDAC4HDAC1HDAC2HDAC8
Fumaric Acid SCHEMBL7709603 0.80 TSHR (0.39) ALDH1A1SMN1; SMN2NPC1
Fumaric Acid SCHEMBL10537007 0.80 TSHR (0.39) ALDH1A1SMN1; SMN2NPC1
Cinnamic Acid SCHEMBL28731806 0.78 HCAR2 (0.86) HCAR2HDAC3HDAC4HDAC1HDAC2
Cinnamic Acid SCHEMBL28030630 0.78 HCAR2 (0.95) HCAR2HDAC3HDAC4HDAC1HDAC2
Cinnamic Acid SCHEMBL50466 0.76 HCAR2 (1.00) HCAR2HDAC3HDAC4HDAC1HDAC2
Cinnamic Acid SCHEMBL1332 0.76 HCAR2 (1.00) HCAR2HDAC3HDAC4HDAC1HDAC2
Cinnamic Acid SCHEMBL1706935 0.76 HCAR2 (1.00) HCAR2HDAC3HDAC4HDAC1HDAC2
Cinnamic Acid SCHEMBL3406486 0.76 HCAR2 (1.00) HCAR2HDAC3HDAC4HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2840432-B1 LIQUID CRYSTAL DISPLAY DEVICE TOPPAN PRINTING CO LTD (JP) 2018-08-08 EP disclosed
US-9508293-B2 Liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2016-11-29 US disclosed
US-9488867-B2 Liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2016-11-08 US disclosed
US-20150070611-A1 LIQUID CRYSTAL DISPLAY DEVICE TOPPAN PRINTING CO., LTD. (JP) 2015-03-12 US disclosed
EP-2840432-A1 LIQUID CRYSTAL DISPLAY DEVICE Toppan Printing Co., Ltd. (JP) 2015-02-25 EP disclosed
US-20150035873-A1 LIQUID CRYSTAL DISPLAY DEVICE TOPPAN PRINTING CO., LTD. (JP) 2015-02-05 US disclosed
CN-104246587-A Liquid crystal display device having a plurality of pixel electrodes TOPPAN PRINTING CO LTD 2014-12-24 CN disclosed
US-6721025-B2 Method for fabricating a liquid crystal cell LG.PHILIPS LCD CO., LTD (KR) 2004-04-13 US disclosed
US-20020171795-A1 Method for fabricating a liquid crystal cell LG DISPLAY CO., LTD. (KR) 2002-11-21 US disclosed
US-6462797-B1 Method for fabricating a liquid crystal cell LG. PHILIPS LCD CO., LTD. (KR) 2002-10-08 US disclosed
US-6417905-B1 Method for fabricating a liquid crystal cell LG. PHILIPS LCD CO., LTD. (KR) 2002-07-09 US disclosed
US-6191836-B1 Method for fabricating a liquid crystal cell LG PHILIPS LCD, CO., LTD. (KR) 2001-02-20 US disclosed