Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 3/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920800 | 0.78 | JAK2 (0.43) | TNKS2CYP1A2KDM4EDAOALDH1A1 | |
| SCHEMBL6923641 | 0.70 | TNKS2 (0.37) | TNKS2DAOTYMPALDH1A1NPC1 | |
| SCHEMBL16320354 | 0.68 | CRBN (0.41) | TNKS2CYP1A2KDM4ECYP2C19TYMP | |
| SCHEMBL2898166 | 0.67 | BRD4 (0.42) | CRBN | |
| SCHEMBL6828447 | 0.66 | PARP1 (0.44) | CYP1A2KDM4EDAOCRBNPARP1 | |
| SCHEMBL7169830 | 0.64 | KDM4E (0.41) | CYP1A2KDM4ECYP2C19PDE3BPDE3A | |
| SCHEMBL10429747 | 0.63 | KDM4E (0.44) | TNKS2CYP1A2KDM4ECYP2C19TYMP | |
| SCHEMBL31392534 | 0.63 | DAO (0.33) | DAOTYMPALDH1A1 | |
| SCHEMBL11242299 | 0.63 | CRBN (0.53) | CYP1A2DAOCRBNPDE2APDE3B | |
| SCHEMBL8404416 | 0.62 | SSTR4 (0.38) | CYP1A2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395585-A1 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002096908-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-12-05 | — | — | WO | disclosed |