Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.52 |
| ▸ | BRD2 | P25440 | 1/20 | 0.52 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.52 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349244 | 0.89 | EGLN1 (0.68) | EGLN1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL19788434 | 0.88 | ATM (0.69) | EGLN1SMN1; SMN2KMT2AMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL6919162 | 0.88 | EGLN1 (0.67) | EGLN1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL19788435 | 0.88 | KDM4E (0.71) | EGLN1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL11454823 | 0.85 | BRD4 (0.68) | SMN1; SMN2KMT2AMEN1KDM4EMAPT | |
| SCHEMBL4992274 | 0.84 | MAPT (0.78) | EGLN1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL3348497 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2AMEN1KDM4EATM | |
| SCHEMBL1770473 | 0.81 | EGLN1 (1.00) | EGLN1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL12599486 | 0.80 | EGLN1 (0.71) | EGLN1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL13306400 | 0.78 | PDPK1 (0.63) | EGLN1SMN1; SMN2KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |