Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.46 |
| ▸ | MASP2 | O00187 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914966 | 1.00 | F2 (0.46) | F2MASP2MEN1KMT2ACYP3A4 | |
| SCHEMBL6914976 | 1.00 | F2 (0.46) | F2MASP2MEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL6919801 | 0.99 | F2 (0.46) | F2MASP2MEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL6919807 | 0.99 | F2 (0.46) | F2MASP2MEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL6920557 | 0.99 | F2 (0.46) | F2MASP2MEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL6920551 | 0.99 | F2 (0.46) | F2MASP2MEN1KMT2ACYP3A4 | |
| SCHEMBL6919181 | 0.88 | F2 (0.41) | F2MASP2CYP3A4F9F10 | |
| SCHEMBL6917428 | 0.88 | F2 (0.41) | F2MASP2CYP3A4F9F10 | |
| SCHEMBL6918683 | 0.85 | F2 (0.56) | F2MASP2CYP3A4F9F10 | |
| SCHEMBL6078060 | 0.83 | F2 (0.49) | F2MASP2MEN1KMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004032834-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2004-04-22 | — | — | WO | disclosed |